WinterPLEX Assay: Your Winter Virus Detection Solution

As winter approaches, the days grow shorter, and the air gets colder. With the change in season comes the inevitable wave of winter viruses, including the flu, RSV, and now, the ongoing threat of COVID-19. These viruses often share similar signs and symptoms, making it challenging to pinpoint the true cause of illness and determine the appropriate course of treatment. In this blog post, we’ll introduce you to an innovative solution that can help healthcare professionals detect and differentiate between these winter viruses efficiently: the WinterPLEX assay (genesigĀ® SARS-CoV-2 WinterPLEX).

The Challenge of Winter Viruses

Winter is notorious for bringing a surge in respiratory illnesses. These illnesses often present with symptoms like fever, cough, and body aches, making it difficult to distinguish one virus from another based on clinical observations alone. In such situations, accurate and rapid diagnostic tests become invaluable to both patients and healthcare providers.

The WinterPLEX Assay

The WinterPLEX assay is a groundbreaking diagnostic tool that allows for the simultaneous real-time PCR detection of multiple winter viruses from a single patient sample. This comprehensive diagnostic assay detects the following viruses:

  1. SARS-CoV-2 (Orf1ab, S, and M genes)
  2. Influenza A
  3. Influenza B
  4. RSV (A & B)

The Benefits of WinterPLEX

  1. Efficiency: With WinterPLEX, healthcare professionals can test for four different winter viruses in one go, saving valuable time and resources. This efficiency can be particularly crucial during the busy winter months when healthcare facilities are often overwhelmed.
  2. Differentiation: WinterPLEX goes beyond simple detection. It can discriminate between Influenza A and Influenza B, providing clinicians with valuable information to tailor their patient care plans effectively.
  3. Compatibility: The WinterPLEX assay is designed for optimal performance and can be seamlessly integrated with a range of PCR instruments, ensuring reliable results without disrupting existing workflows and routines.
  4. Annual Updates: To stay ahead of viral mutations and evolving strains, the WinterPLEX assay is reviewed annually and updated as necessary. This ensures that it continues to detect the current circulating strains of the viruses accurately.
  5. High Sensitivity: WinterPLEX boasts high sensitivity and a broad detection profile, enhancing its clinical utility.
  6. Lyophilized Master Mix: The lyophilized qPCR Master Mix used in WinterPLEX eliminates the need for cold chain shipping, simplifying the logistics of distributing and using the assay.

Maximizing Testing Efficiency

One of the standout features of WinterPLEX is its standard reaction parameters, allowing for batch testing. This streamlines the testing process, enabling healthcare facilities to process multiple samples efficiently. This enhanced efficiency can be a game-changer in managing patient loads during the peak of the winter virus season.

Enhanced Clinical Utility

Recent studies have highlighted the differences between Influenza A and Influenza B, with Flu A often showing greater severity and a dynamic, faster-changing nature. WinterPLEX’s ability to differentiate between these two strains equips clinicians with essential information to guide patient treatment decisions effectively.


As winter approaches, the specter of multiple winter viruses looms large. The WinterPLEX assay offers healthcare professionals a powerful tool to detect and differentiate between these viruses efficiently. With its high sensitivity, broad detection profile, and compatibility with existing laboratory systems, WinterPLEX is a valuable addition to the arsenal of tools available for managing winter illnesses. By providing precise, reproducible results, WinterPLEX helps healthcare providers protect their patients and communities, ultimately contributing to better patient outcomes during the challenging winter months.

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